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In a posting to the Guile developers listtoday, it was announced that the Emacs-Lispcompiler for Guile has matured enough to run actual elispprograms. The author included a screencast demoingthe new compiler running the Dunnetdungeon crawler. It is still a bit hackish: you need a load file that fakes a few Emacs side functions. In theory, most batch mode programs that don't do buffer manipulation should now work. After a few previous attempts, things could be on track for GNU Emacs 25 based on Guile.
Guile Scheme Emacs-Lisp Compatibility Matures
Threaded Mode